Wednesday, May 13, 2020
Article Review - 1471 Words
ââ¬Å"Physicians themselves are notoriously bad at estimating prognosis in patients with cancer, and overly optimistic estimates can influence patientsââ¬â¢ chemotherapy decisionsâ⬠(Obermyer, 2017, p. 3). As such, it is imperative that an accurate means of predicting patientsââ¬â¢ risks and outcomes with regards to chemotherapy be found and used in clinical application. The three articles studied in this review use very different methods of predicting patient outcomes, and prove more accurate than the current ââ¬Å"predictions... from randomized trials of individual chemotherapies, or SEER (Surveillance, Epidemiology and End Results) estimatesâ⬠(Obermyer, 2017, p. 18). Regardless of their apparent successes, there is room for improvement in all threeâ⬠¦show more contentâ⬠¦The Harvard team also generalized cancer into only 6 sub-categories: colorectal, non-small cell lung cancer, small cell lung cancer, squamous cell carcinoma, breast and prostate cancer. It would be interesting to see if the accuracy of the machine learning algorithm would increase with increased specificity of diagnosis of cancer. Overall, this study had an extraordinarily large data set (7000+) and their analyses of the data is well planned. That said, more in-depth categorization of cancers and further data with regards to overall patient health during and before diagnosis, prior to treatment, would prove immensely informative and helpful. The second article, ââ¬Å"A framework to translate preclinical findings to the clinicâ⬠, created a ââ¬Å"computational framework to implement phase i trials (virtual/imaginary yet informed clinical trials) using an experimentally calibrated mathematical model of melanoma combination therapyâ⬠(Kim, 2015, p. 2). In other words, they developed one program to generate virtual heterogeneous patients (similar to what would be used in clinical trials) whom they would then subject to chemotherapy under different living conditions according to their mathematical model and optimal treatment strategy. The studyââ¬â¢s ultimate goal being to develop the most effective treatment of cancer for each individual patient. As the patient body was entirely virtual aside from in-vitro experimentation, they were ableShow MoreRelatedSample Article Review1246 Words à |à 5 Pagese Article review : Sample 1 Source Bell, R.L. Lederman. (2003). Understandings of the nature of science and decision making on science and technology based issues. 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In this article, William Baker also described to us, the relationship between the ancient Olympic Games, and Greek religion, what some of the Greek philosophers thought of the Olympic Games, and the role of athletics in general, in ancient Greek Society. William Bakerââ¬â¢s article, ââ¬Å"OrganizedRead MoreArticle Review1507 Words à |à 7 PagesFirst educational researchers realize that scientific methods of research do not adequately measure what is happening in the classroom. Secondly, new technologies have led to new classroom activities that necessitate new methods of analysis. This article suggests that if current tr ends continue, descriptive research methodology will grow in popularity and use.Read MoreArticle Review783 Words à |à 4 PagesMindByte #3 Matteo Rocco Lawrence Caprio I want you to read the following article,â⬠How statistical deception created the appearance that statins are safe and effective in primary and secondary prevention of cardiovascular diseaseâ⬠, David m. Diamond and Uffe Ravnskov; Expert Rev. Clin. Pharmacol. Early inline, 1-10 (2015) a) On the first page, Hillââ¬â¢s criteria for causality is referenced. I now want you to research the term; ââ¬Å"(Bradford) Hillââ¬â¢s criteria for causalityâ⬠and list six of the possible
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